Parkinson's Escape: Smoking Or Alcohol?

Original posting, February 2006

The report below outlines some interesting commentary about a possible link between smoking, alcohol and Parkinson’s disease. My additional commentary is simple: Parkinson’s Disease is generally amongst the older generation. Those who smoke AND drink. Imagine a binge-drinking pensioner as the norm. Such an individual will probably have died before they get the disease. Remember the ‘cynical’ comment about cigarettes being the perfect product: take your money while you are working and paying tax upon tax, then when you die before you get ill, the State is denied the opportunity to 'support' your ill-health and 'making' money out of you as you live on. Also a very good reason to make everyone live longer by extending life (being alive does not require your good health. When you die there is no on-cost - DA). Caused by the State encouraging (or rather not discouraging) these dangerous habits. It is very cost-effective.

People who take more risks with their health (including smoking and drinking) are less likely to develop Parkinson's disease, a study suggests.

Mind you, rocket science is never easy, but let's try.

They die before they get Parkinson's disease.

A team led by the University of London quizzed 212 people - half of whom had Parkinson's - and identified a risk-averse "Parkinsonian Personality".

Smokers and drinkers seemed to be protected - maybe because these habits denoted a risk-taking personality.

Parkinson's disease experts said the results should be treated with caution.

The study appeared in the Journal of Neurology, Neurosurgery and Psychiatry.

Who sponsored the study?

Certain personality characteristics of individuals destined to develop Parkinson's disease may make them less prone to start smoking. Parkinson's is a degenerative brain disorder which affects movement and becomes more common in older age. Its causes remain unclear, but it is often associated with a shortage of the brain chemical dopamine which controls connections between nerve cells.

Cause unclear, but something to do with personality characteristics.

Earlier studies suggest a link between smoking and caffeine intake and lower rates of Parkinson's. And it has been suggested the dopamine system is protected by nicotine and caffeine.

Professor Andrew Lees of the University of London, who led the research, said:

• "If you have never smoked you have double the risk of Parkinson's disease but we do not know the reasons for that. It may be that there's something protective within cigarette smoking or it may be another factor. Certain personality characteristics of individuals destined to develop Parkinson's disease may make them less prone to start smoking."

The study found patients with Parkinson's disease had smoked less, drank less alcohol and caffeine.

• This suggests that if you want to minimise the chances of Parkinsonism in old age, you'd better take up smoking and drinking while you're younger. It just happens you'd pay a lot of tax when younger and then die before you start costing too much.

Who sponsored this?

They also scored lower on sensation-seeking and risk taking behaviour, and higher on anxiety and depression than the comparison group.

This prompted the authors to suggest there may be a link between low sensation-seeking behaviour and what might be termed a "Parkinsonian Personality".

They draw on earlier studies which suggest Parkinson's disease patients tend to reject hedonistic behaviour, to be scrupulous, socially withdrawn and disinclined to take risks.

So if you reject hedonistic behaviour (devoted to pleasure) you are socially withdrawn. And by being careful you do not take risks.

What an unusual type.

They suggested it may be the risk-averse nature of the "Parkinsonian Personality", rather than the physical effects of smoking, caffeine and alcohol on the brain that influences disease rates.

Professor Lees acknowledged that behaviour may be being affected by something going wrong in the dopamine system long before symptoms of the disease materialised.

However, he added that there was evidence that certain personality types were more likely to develop certain diseases.

Kieran Breen, research director at the Parkinson's Disease Society, said determining cause and effect in retrospective studies such as this is extremely difficult and highly unreliable.

• As dopamine levels can start to fall many years before difficulties with movement become noticeable and before a diagnosis of Parkinson's disease is made, an assumption that the personality traits outlined in the study cause the condition is flawed.
• ... research which implies that people with Parkinson's have set characteristics or lifestyles must be treated with caution.
• A more likely explanation would be that declining dopamine levels prior to the onset of the motor symptoms is associated with these behaviours.

Dr Paul Wicks, research psychologist at the Institute of Psychiatry, said the theory was interesting but that it needed to be tested in a long-term study.

• "Needless to say for all the pleasure they bring there are a multitude of other health risks, associated with nicotine, alcohol, and caffeine."
• "I hope we won't be seeing headlines suggesting everyone start binge-drinking, chain-smoking, and knocking back espressos to ward off Parkinson's disease."

This last comment seems the most sensible.

Anyone for sponsorship by BAT or the like?